Table of contentsI1 Proceedings of the 4th World Conference on Research IntegrityConcurrent Sessions:1. Countries' systems and policies to foster research integrityCS01.1 Second time around: Implementing and embedding a review of responsible conduct of research policy and practice in an Australian research-intensive universitySusan Patricia O'BrienCS01.2 Measures to promote research integrity in a university: the case of an Asian universityDanny Chan, Frederick Leung2. Examples of research integrity education programmes in different countriesCS02.1 Development of a state-run “cyber education program of research ethics” in (...) KoreaEun Jung Ko, Jin Sun Kwak, TaeHwan Gwon, Ji Min Lee, Min-Ho LeeCS02.3 Responsible conduct of research teachers’ training courses in Germany: keeping on drilling through hard boards for more RCR teachersHelga Nolte, Michael Gommel, Gerlinde Sponholz3. The research environment and policies to encourage research integrityCS03.1 Challenges and best practices in research integrity: bridging the gap between policy and practiceYordanka Krastev, Yamini Sandiran, Julia Connell, Nicky SolomonCS03.2 The Slovenian initiative for better research: from national activities to global reflectionsUrsa Opara Krasovec, Renata SribarCS03.3 Organizational climate assessments to support research integrity: background of the Survey of Organizational Research Climate and the experience with its use at Michigan State UniversityBrian C. Martinson, Carol R. Thrush, C.K. Gunsalus4. Expressions of concern and retractionsCS04.1 Proposed guidelines for retraction notices and their disseminationIvan Oransky, Adam MarcusCS04.2 Watching retractions: analysis of process and practice, with data from the Wiley retraction archivesChris Graf, Verity Warne, Edward Wates, Sue JoshuaCS04.3 An exploratory content analysis of Expressions of ConcernMiguel RoigCS04.4 An ethics researcher in the retraction processMichael Mumford5. Funders' role in fostering research integrityCS05.1 The Fonds de Recherche du Québec’s institutional rules on the responsible conduct of research: introspection in the funding agency activitiesMylène Deschênes, Catherine Olivier, Raphaëlle Dupras-LeducCS05.2 U.S. Public Health Service funds in an international setting: research integrity and complianceZoë Hammatt, Raju Tamot, Robin Parker, Cynthia Ricard, Loc Nguyen-Khoa, Sandra TitusCS05.3 Analyzing decision making of funders of public research as a case of information asymmetryKarsten Klint JensenCS05.4 Research integrity management: Empirical investigation of academia versus industrySimon Godecharle, Ben Nemery, Kris Dierickx5A: Education: For whom, how, and what?CS05A.1 Research integrity or responsible conduct of research? What do we aim for?Mickey Gjerris, Maud Marion Laird Eriksen, Jeppe Berggren HoejCS05A.2 Teaching and learning about RCR at the same time: a report on Epigeum’s RCR poll questions and other assessment activitiesNicholas H. SteneckCS05A.4 Minding the gap in research ethics education: strategies to assess and improve research competencies in community health workers/promoteresCamille Nebeker, Michael Kalichman, Elizabeth Mejia Booen, Blanca Azucena Pacheco, Rebeca Espinosa Giacinto, Sheila Castaneda6. Country examples of research reward systems and integrityCS06.1 Improving systems to promote responsible research in the Chinese Academy of SciencesDing Li, Qiong Chen, Guoli Zhu, Zhonghe SunCS06.4 Exploring the perception of research integrity amongst public health researchers in IndiaParthasarathi Ganguly, Barna Ganguly7. Education and guidance on research integrity: country differencesCS07.1 From integrity to unity: how research integrity guidance differs across universities in Europe.Noémie Aubert Bonn, Kris Dierickx, Simon GodecharleCS07.2 Can education and training develop research integrity? The spirit of the UNESCO 1974 recommendation and its updatingDaniele Bourcier, Jacques Bordé, Michèle LeducCS07.3 The education and implementation mechanisms of research ethics in Taiwan's higher education: an experience in Chinese web-based curriculum development for responsible conduct of researchChien Chou, Sophia Jui-An PanCS07.4 Educating principal investigators in Swiss research institutions: present and future perspectivesLouis Xaver Tiefenauer8. Measuring and rewarding research productivityCS08.1 Altimpact: how research integrity underpins research impactDaniel Barr, Paul TaylorCS08.2 Publication incentives: just reward or misdirection of funds?Lyn Margaret HornCS08.3 Why Socrates never charged a fee: factors contributing to challenges for research integrity and publication ethicsDeborah Poff9. Plagiarism and falsification: Behaviour and detectionCS09.1 Personality traits predict attitude towards plagiarism of self and others in biomedicine: plagiarism, yes we can?Martina Mavrinac, Gordana Brumini, Mladen PetrovečkiCS09.2 Investigating the concept of and attitudes toward plagiarism for science teachers in Brazil: any challenges for research integrity and policy?Christiane Coelho Santos, Sonia VasconcelosCS09.3 What have we learnt?: The CrossCheck Service from CrossRefRachael LammeyCS09.4 High p-values as a sign of data fabrication/falsificationChris Hartgerink, Marcel van Assen, Jelte Wicherts10. Codes for research integrity and collaborationsCS10.1 Research integrity in cross-border cooperation: a Nordic exampleHanne Silje HaugeCS10.3 Research integrity, research misconduct, and the National Science Foundation's requirement for the responsible conduct of researchAaron MankaCS10.4 A code of conduct for international scientific cooperation: human rights and research integrity in scientific collaborations with international academic and industry partnersRaffael Iturrizaga11. Countries' efforts to establish mentoring and networksCS11.1 ENRIO : a network facilitating common approaches on research integrity in EuropeNicole FoegerCS11.2 Helping junior investigators develop in a resource-limited country: a mentoring program in PeruA. Roxana Lescano, Claudio Lanata, Gissella Vasquez, Leguia Mariana, Marita Silva, Mathew Kasper, Claudia Montero, Daniel Bausch, Andres G LescanoCS11.3 Netherlands Research Integrity Network: the first six monthsFenneke Blom, Lex BouterCS11.4 A South African framework for research ethics and integrity for researchers, postgraduate students, research managers and administratorsLaetus OK Lategan12. Training and education in research integrity at an early career stageCS12.1 Research integrity in curricula for medical studentsGustavo Fitas ManaiaCS12.2 Team-based learning for training in the responsible conduct of research supports ethical decision-makingWayne T. McCormack, William L. Allen, Shane Connelly, Joshua Crites, Jeffrey Engler, Victoria Freedman, Cynthia W. Garvan, Paul Haidet, Joel Hockensmith, William McElroy, Erik Sander, Rebecca Volpe, Michael F. VerderameCS12.4 Research integrity and career prospects of junior researchersSnezana Krstic13. Systems and research environments in institutionsCS13.1 Implementing systems in research institutions to improve quality and reduce riskLouise HandyCS13.2 Creating an institutional environment that supports research integrityDebra Schaller-DemersCS13.3 Ethics and Integrity Development Grants: a mechanism to foster cultures of ethics and integrityPaul Taylor, Daniel BarrCS13.4 A culture of integrity at KU LeuvenInge Lerouge, Gerard Cielen, Liliane Schoofs14. Peer review and its role in research integrityCS14.1 Peer review research across disciplines: transdomain action in the European Cooperation in Science and Technology “New Frontiers of Peer Review ”Ana Marusic, Flaminio SquazzoniCS14.2 Using blinding to reduce bias in peer reviewDavid VauxCS14.3 How to intensify the role of reviewers to promote research integrityKhalid Al-Wazzan, Ibrahim AlorainyCS14.4 Credit where credit’s due: professionalizing and rewarding the role of peer reviewerChris Graf, Verity Warne15. Research ethics and oversight for research integrity: Does it work?CS15.1 The psychology of decision-making in research ethics governance structures: a theory of bounded rationalityNolan O'Brien, Suzanne Guerin, Philip DoddCS15.2 Investigator irregularities: iniquity, ignorance or incompetence?Frank Wells, Catherine BlewettCS15.3 Academic plagiarismFredric M. Litto16. Research integrity in EuropeCS16.1 Whose responsibility is it anyway?: A comparative analysis of core concepts and practice at European research-intensive universities to identify and develop good practices in research integrityItziar De Lecuona, Erika Löfstrom, Katrien MaesCS16.2 Research integrity guidance in European research universitiesKris Dierickx, Noémie Bonn, Simon GodecharleCS16.3 Research Integrity: processes and initiatives in Science Europe member organisationsTony Peatfield, Olivier Boehme, Science Europe Working Group on Research IntegrityCS16.4 Promoting research integrity in Italy: the experience of the Research Ethics and Bioethics Advisory Committee of the Consiglio Nazionale delle Ricerche Cinzia Caporale, Daniele Fanelli17. Training programs for research integrity at different levels of experience and seniorityCS17.1 Meaningful ways to incorporate research integrity and the responsible conduct of research into undergraduate, graduate, postdoctoral and faculty training programsJohn Carfora, Eric Strauss, William LynnCS17.2 "Recognize, respond, champion": Developing a one-day interactive workshop to increase confidence in research integrity issuesDieter De Bruyn, Bracke Nele, Katrien De Gelder, Stefanie Van der BurghtCS17.4 “Train the trainer” on cultural challenges imposed by international research integrity conversations: lessons from a projectJosé Roberto Lapa e Silva, Sonia M. R. Vasconcelos18. Research and societal responsibilityCS18.1 Promoting the societal responsibility of research as an integral part of research integrityHelene IngierdCS18.2 Social responsibility as an ethical imperative for scientists: research, education and service to societyMark FrankelCS18.3 The intertwined nature of social responsibility and hope in scienceDaniel Vasgird, Stephanie BirdCS18.4 Common barriers that impede our ability to create a culture of trustworthiness in the research communityMark Yarborough19. Publication ethicsCS19.1 The authors' forum: A proposed tool to improve practices of journal editors and promote a responsible research environmentIbrahim Alorainy, Khalid Al-WazzanCS19.2 Quantifying research integrity and its impact with text analyticsHarold GarnerCS19.3 A closer look at authorship and publication ethics of multi- and interdisciplinary teamsLisa Campo-Engelstein, Zubin Master, Elise Smith, David Resnik, Bryn Williams-JonesCS19.4 Invisibility of duplicate publications in biomedicineMario Malicki, Ana Utrobicic, Ana Marusic20. The causes of bad and wasteful research: What can we do?CS20.1 From countries to individuals: unravelling the causes of bias and misconduct with multilevel meta-meta-analysisDaniele Fanelli, John PA IoannidisCS20.2 Reducing research waste by integrating systems of oversight and regulationGerben ter Riet, Tom Walley, Lex Marius BouterCS20.3 What are the determinants of selective reporting?: The example of palliative care for non-cancer conditionsJenny van der Steen, Lex BouterCS20.4 Perceptions of plagiarism, self-plagiarism and redundancy in research: preliminary results from a national survey of Brazilian PhDsSonia Vasconcelos, Martha Sorenson, Francisco Prosdocimi, Hatisaburo Masuda, Edson Watanabe, José Carlos Pinto, Marisa Palácios, José Lapa e Silva, Jacqueline Leta, Adalberto Vieyra, André Pinto, Mauricio Sant’Ana, Rosemary Shinkai21. Are there country-specific elements of misconduct?CS21.1 The battle with plagiarism in Russian science: latest developmentsBoris YudinCS21.2 Researchers between ethics and misconduct: A French survey on social representations of misconduct and ethical standards within the scientific communityEtienne Vergès, Anne-Sophie Brun-Wauthier, Géraldine VialCS21.3 Experience from different ways of dealing with research misconduct and promoting research integrity in some Nordic countriesTorkild VintherCS21.4 Are there specifics in German research misconduct and the ways to cope with it?Volker Bähr, Charité22. Research integrity teaching programmes and their challengesCS22.1 Faculty mentors and research integrityMichael Kalichman, Dena PlemmonsCS22.2 Training the next generation of scientists to use principles of research quality assurance to improve data integrity and reliabilityRebecca Lynn Davies, Katrina LaubeCS22.3 Fostering research integrity in a culturally-diverse environmentCynthia Scheopner, John GallandCS22.4 Towards a standard retraction formHervé Maisonneuve, Evelyne Decullier23. Commercial research and integrityCS23.1 The will to commercialize: matters of concern in the cultural economy of return-on-investment researchBrian NobleCS23.2 Quality in drug discovery data reporting: a mission impossible?Anja Gilis, David J. Gallacher, Tom Lavrijssen, Malwitz David, Malini Dasgupta, Hans MolsCS23.3 Instituting a research integrity policy in the context of semi-private-sector funding: an example in the field of occupational health and safetyPaul-Emile Boileau24. The interface of publication ethics and institutional policiesCS24.1 The open access ethical paradox in an open government effortTony SavardCS24.2 How journals and institutions can work together to promote responsible conductEric MahCS24.3 Improving cooperation between journals and research institutions in research integrity casesElizabeth Wager, Sabine Kleinert25. Reproducibility of research and retractionsCS25.1 Promoting transparency in publications to reduce irreproducibilityVeronique Kiermer, Andrew Hufton, Melanie ClyneCS25.2 Retraction notices issued for publications by Latin American authors: what lessons can we learn?Sonia Vasconcelos, Renan Moritz Almeida, Aldo Fontes-Pereira, Fernanda Catelani, Karina RochaCS25.3 A preliminary report of the findings from the Reproducibility Project: Cancer biologyElizabeth Iorns, William Gunn26. Research integrity and specific country initiativesCS26.1 Promoting research integrity at CNRS, FranceMichèle Leduc, Lucienne LetellierCS26.2 In pursuit of compliance: is the tail wagging the dog?Cornelia MalherbeCS26.3 Newly established research integrity policies and practices: oversight systems of Japanese research universitiesTakehito Kamata27. Responsible conduct of research and country guidelinesCS27.1 Incentives or guidelines? Promoting responsible research communication through economic incentives or ethical guidelines?Vidar EnebakkCS27.3 Responsible conduct of research: a view from CanadaLynn PenrodCS27.4 The Danish Code of Conduct for Research Integrity: a national initiative to promote research integrity in DenmarkThomas Nørgaard, Charlotte Elverdam28. Behaviour, trust and honestyCS28.1 The reasons behind non-ethical behaviour in academiaYves FassinCS28.2 The psychological profile of the dishonest scholarCynthia FekkenCS28.3 Considering the implications of Dan Ariely’s keynote speech at the 3rd World Conference on Research Integrity in MontréalJamal Adam, Melissa S. AndersonCS28.4 Two large surveys on psychologists’ views on peer review and replicationJelte WichertsBrett Buttliere29. Reporting and publication bias and how to overcome itCS29.1 Data sharing: Experience at two open-access general medical journalsTrish GrovesCS29.2 Overcoming publication bias and selective reporting: completing the published recordDaniel ShanahanCS29.3 The EQUATOR Network: promoting responsible reporting of health research studiesIveta Simera, Shona Kirtley, Eleana Villanueva, Caroline Struthers, Angela MacCarthy, Douglas Altman30. The research environment and its implications for integrityCS30.1 Ranking of scientists: the Russian experienceElena GrebenshchikovaCS30.4 From cradle to grave: research integrity, research misconduct and cultural shiftsBronwyn Greene, Ted RohrPARTNER SYMPOSIAPartner Symposium AOrganized by EQUATOR Network, Enhancing the Quality and Transparency of Health ResearchP1 Can we trust the medical research literature?: Poor reporting and its consequencesIveta SimeraP2 What can BioMed Central do to improve published research?Daniel Shanahan, Stephanie HarrimanP3 What can a "traditional" journal do to improve published research?Trish GrovesP4 Promoting good reporting practice for reliable and usable research papers: EQUATOR Network, reporting guidelines and other initiativesCaroline StruthersPartner Symposium COrganized by ENRIO, the European Network of Research Integrity OfficersP5 Transparency and independence in research integrity investigations in EuropeKrista Varantola, Helga Nolte, Ursa Opara, Torkild Vinther, Elizabeth Wager, Thomas NørgaardPartner Symposium DOrganized by IEEE, the Institute of Electrical and Electronics EngineersRe-educating our author community: IEEE's approach to bibliometric manipulation, plagiarism, and other inappropriate practicesP6 Dealing with plagiarism in the connected world: An Institute of Electrical and Electronics Engineers perspectiveJon RokneP7 Should evaluation of raises, promotion, and research proposals be tied to bibliometric indictors? What the Institute of Electrical and Electronics Engineers is doing to answer this questionGianluca SettiP8 Recommended practices to ensure conference content qualityGordon MacPhersonPartner Symposium EOrganized by the Committee on Freedom and Responsibility in the Conduct of Science of ICSU, the International Council for ScienceResearch assessment and quality in science: perspectives from international science and policy organisationsP9 Challenges for science and the problems of assessing researchEllen HazelkornP10 Research assessment and science policy developmentCarthage SmithP11 Research integrity in South Africa: the value of procedures and processes to global positioningRobert H. McLaughlinP12 Rewards, careers and integrity: perspectives of young scientists from around the worldTatiana Duque MartinsPartner Symposium FOrganized by the Online Resource Center for Ethics Education in Engineering and Science / Center for Engineering, Ethics, and Society of the National Academy of EngineeringP13 Research misconduct: conceptions and policy solutionsTetsuya Tanimoto, Nicholas Steneck, Daniele Fanelli, Ragnvald Kalleberg, Tajammul HusseinPartner Symposium HOrganized by ORI, the Office of Research Integrity; Universitas 21; and the Asia Pacific Research Integrity NetworkP14 International integrity networks: working together to ensure research integrityPing Sun, Ovid Tzeng, Krista Varantola, Susan ZimmermanPartner Symposium IOrganized by COPE, the Committee on Publication EthicsPublication without borders: Ethical challenges in a globalized worldP15 Authorship: credit and responsibility, including issues in large and interdisciplinary studiesRosemary ShinkaiPartner Symposium JOrganized by CITI, the Cooperative Institutional Training InitiativeExperiences on research integrity educational programs in Colombia, Costa Rica and PeruP16 Experiences in PeruRoxana LescanoP17 Experiences in Costa RicaElizabeth HeitmanP18 Experiences in ColumbiaMaria Andrea Rocio del Pilar Contreras NietoPoster Session B: Education, training, promotion and policyPT.01 The missing role of journal editors in promoting responsible researchIbrahim Alorainy, Khalid Al-WazzanPT.02 Honorary authorship in Taiwan: why and who should be in charge?Chien Chou, Sophia Jui-An PanPT.03 Authorship and citation manipulation in academic researchEric Fong, Al WilhitePT.04 Open peer review of research submission at medical journals: experience at BMJ Open and The BMJTrish GrovesPT.05 Exercising authorship: claiming rewards, practicing integrityDésirée Motta-RothPT.07 Medical scientists' views on publication culture: a focus group studyJoeri Tijdink, Yvo SmuldersPoster Session B: Education, training, promotion and policyPT.09 Ethical challenges in post-graduate supervisionLaetus OK LateganPT.10 The effects of viable ethics instruction on international studentsMichael Mumford, Logan Steele, Logan Watts, James Johnson, Shane Connelly, Lee WilliamsPT.11 Does language reflect the quality of research?Gerben ter Riet, Sufia Amini, Lotty Hooft, Halil KilicogluPT.12 Integrity complaints as a strategic tool in policy decision conflictsJanneke van Seters, Herman Eijsackers, Fons Voragen, Akke van der Zijpp and Frans BromPoster Session C: Ethics and integrity intersectionsPT.14 Regulations of informed consent: university-supported research processes and pitfalls in implementationBadaruddin Abbasi, Naif Nasser AlmasoudPT.15 A review of equipoise as a requirement in clinical trialsAdri LabuschagnePT.16 The Research Ethics Library: online resource for research ethics educationJohanne Severinsen, Espen EnghPT.17 Research integrity: the view from King Abdulaziz City for Science and TechnologyDaham Ismail AlaniPT. 18 Meeting global challenges in high-impact publications and research integrity: the case of the Malaysian Palm Oil BoardHJ. Kamaruzaman JusoffPT.19 University faculty perceptions of research practices and misconductAnita Gordon, Helen C. HartonPoster Session D: International perspectivesPT.21 The Commission for Scientific Integrity as a response to research fraudDieter De Bruyn, Stefanie Van der BurghtPT. 22 Are notions of the responsible conduct of research associated with compliance with requirements for research on humans in different disciplinary traditions in Brazil?Karina de Albuquerque Rocha, Sonia Maria Ramos de VasconcelosPT.23 Creating an environment that promotes research integrity: an institutional model of Malawi Liverpool Welcome TrustLimbanazo MatandikaPT.24 How do science policies in Brazil influence user-engaged ecological research?Aline Carolina de Oliveira Machado Prata, Mark William NeffPoster Session E: Perspectives on misconductPT.26 What “causes” scientific misconduct?: Testing major hypotheses by comparing corrected and retracted papersDaniele Fanelli, Rodrigo Costas, Vincent LarivièrePT.27 Perception of academic plagiarism among dentistry studentsDouglas Leonardo Gomes Filho, Diego Oliveira GuedesPT. 28 a few bad apples?: Prevalence, patterns and attitudes towards scientific misconduct among doctoral students at a German university hospitalVolker Bähr, Niklas Keller, Markus Feufel, Nikolas OffenhauserPT. 29 Analysis of retraction notices published by BioMed CentralMaria K. Kowalczuk, Elizabeth C. MoylanPT.31 "He did it" doesn't work: data security, incidents and partnersKatie SpeanburgPoster Session F: Views from the disciplinesPT.32 Robust procedures: a key to generating quality results in drug discoveryMalini Dasgupta, Mariusz Lubomirski, Tom Lavrijssen, David Malwitz, David Gallacher, Anja GillisPT.33 Health promotion: criteria for the design and the integrity of a research projectMaria Betânia de Freitas Marques, Laressa Lima Amâncio, Raphaela Dias Fernandes, Oliveira Patrocínio, and Cláudia Maria Correia Borges RechPT.34 Integrity of academic work from the perspective of students graduating in pharmacy: a brief research studyMaria Betânia de Freitas Marques, Cláudia Maria Correia Borges Rech, Adriana Nascimento SousaPT.35 Research integrity promotion in the Epidemiology and Health Services, the journal of the Brazilian Unified Health SystemLeila Posenato GarciaPT.36 When are clinical trials registered? An analysis of prospective versus retrospective registration of clinical trials published in the BioMed Central series, UKStephanie Harriman, Jigisha PatelPT.37 Maximizing welfare while promoting innovation in drug developmentFarida LadaOther posters that will be displayed but not presented orally:PT.38 Geoethics and the debate on research integrity in geosciencesGiuseppe Di Capua, Silvia PeppoloniPT.39 Introducing the Professionalism and Integrity in Research Program James M. DuBois, John Chibnall, Jillon Van der WallPT.40 Validation of the professional decision-making in research measureJames M. DuBois, John Chibnall, Jillon Van der Wall, Raymond TaitPT.41 General guidelines for research ethicsJacob HolenPT. 42 A national forum for research ethicsAdele Flakke Johannessen, Torunn EllefsenPT.43 Evaluation of integrity in coursework: an approach from the perspective of the higher education professorClaudia Rech, Adriana Sousa, Maria Betânia de Freitas MarquesPT.44 Principles of geoethics and research integrity applied to the European Multidisciplinary Seafloor and Water Column Observatory, a large-scale European environmental research infrastructureSilvia Peppoloni, Giuseppe Di Capua, Laura BeranzoliF1 Focus track on improving research systems: the role of fundersPaulo S.L. Beirão, Susan ZimmermanF2 Focus track on improving research systems: the role of countriesSabine Kleinert, Ana MarusicF3 Focus track on improving research systems: the role of institutionsMelissa S. Anderson, Lex Bouter. (shrink)

Features of threatening cues and the associated context influence the perceived imminence of threat and the defensive responses evoked. To provide additional knowledge about how the directionality of a threat (i.e. directed-towards or away from the viewer) might impact defensive responses in humans, participants were shown pictures of a man carrying a gun (threat) or nonlethal object (neutral) directed-away from or towards the participant. Cardiac and electrodermal responses were collected. Compared to neutral images, threatening images depicting a gun directed-towards the (...) participant induced sustained bradycardia and an increased electrodermal response, interpreted as immobility under attack. This defensive immobility reaction is evoked by high perceived threat and inescapable situations and indicates intense action preparation. Pictures of guns directed-away from the participant induced shorter bradycardia and no significant modulation of the electrodermal response compared to neutral pictures, which might be consistent with the perception of a less threatening situation. The results show that the directionality of threat stimuli is a key factor that prompts different patterns of defensive responses. (shrink)

NIK1 is a receptor‐like kinase involved in plant antiviral immunity. Although NIK1 is structurally similar to the plant immune factor BAK1, which is a key regulator in plant immunity to bacterial pathogens, the NIK1‐mediated defenses do not resemble BAK1 signaling cascades. The underlying mechanism for NIK1 antiviral immunity has recently been uncovered. NIK1 activation mediates the translocation of RPL10 to the nucleus, where it interacts with LIMYB to fully down‐regulate translational machinery genes, resulting in translation inhibition of host and viral (...) mRNAs and enhanced tolerance to begomovirus. Therefore, the NIK1 antiviral immunity response culminates in global translation suppression, which represents a new paradigm for plant antiviral defenses. Interestingly, transcriptomic analyses in nik1 mutant suggest that NIK1 may suppress antibacterial immune responses, indicating a possible opposite effect of NIK1 in bacterial and viral infections. (shrink)

O objetivo deste trabalho consiste em apresentar algumas mudanças promovidas por Hobbes entre Elementos da Lei e as edições inglesas de Leviatã e De Corpore no que diz respeito à sua teoria da linguagem. Sustenta-se que não é possível conceber uma unidade entre todas as obras supracitadas e que De Corpore contém a versão final da teoria da linguagem hobbesiana; e sugere-se que as alterações promovidas se devem, ao menos em parte, às críticas que Descartes promove nas respostas às Terceiras (...) Objeções e à adoção, a partir de 1651, da geometria, enquanto método, na teoria da linguagem. (shrink)

Apresentamos os resultados de uma pesquisa qualitativa, envolvendo a elaboração e aplicação de uma sequência didática numa escola pública do Estado da Bahia, Brasil, localizada no contexto de comunidades tradicionais. Os dados foram coletados após a aplicação de uma sequência didática que gerou a oportunidade de tomada de decisão por parte dos estudantes diante de uma problemática dos transgênicos, relacionada ao seu cotidiano. Os resultados mostram os níveis e estágios de letramento científico alcançados por cada grupo e foram analisados a (...) partir do modelo proposto por Conrado. Os grupos apresentaram dificuldades argumentativas, no entanto, as decisões apresentadas demonstram o exercício da criticidade, importante para as tomadas de decisões reais em seu cotidiano. Dessa forma, o presente trabalho permitiu realizar reflexões sobre o que pode ser melhorado na sequência didática no que tange a sua abordagem, visando ampliar os níveis e estágios de letramento alcançados pelos estudantes e abrindo margem para trabalhos futuros contendo ajustes que contribuam para o desenvolvimento da criticidade por parte dos estudantes. (shrink)

O discurso didático que a escola vem construindo ao longo da história da educação brasileira tem em seu bojo o centralismo epistemológico eurocêntrico institucionalizado. Sendo assim, entendemos ser necessário a constante problematização em torno desses discursos na ação docente. Neste artigo, temos como objetivo analisar a forma como são discursivizadas a História e Cultura Afro-Brasileiras, Africanas, e Indígenas no discurso didático do livro de Física do Ensino Médio Integrado ao Técnico em uso no IFBA, campus Eunápolis. Realizamos uma pesquisa bibliográfica (...) por meio da análise de um corpus constituído de materialidades advindas da coleção, Compreendendo a Física, Alberto Gaspar – 3. ed. – São Paulo: Ática, 2016. Para isso mobilizamos a análise do discurso de linha francesa, as teorias fundantes desta pesquisa de perspectiva multicultural e decolonial, bem como discussões acerca do Livro Didático, esse aparato didático tão presente nas salas de aula e tão pouco consensual. Os resultados apontam que o discurso didático da coleção analisada, não se movimenta para a efetivação de fato da legislação específica do Ensino de História e Cultura Afro-brasileira na rede regular de educação básica. Por isso podemos afirmar que há necessidade de ampliação no plano conceitual e epistemológico do que significa construir uma proposta didática sob a perspectiva racial, que considere para o ensino de Física, as epistemologias africanas e indígenas que potencializam a descolonização deste artefato cultural. Palavras-chave: Relações étnico-raciais. Livro didático. Descolonização. Discurso didático. (shrink)

O objetivo desse artigo é apresentar os desafios e as possibilidades de se desenvolver – em contextos formativos que discutem o ensino da matemática sob a perspectiva da Educação Matemática Crítica – um processo de empoderamento docente por intermédio de uma prática educativa libertadora com professoras dos anos iniciais do Ensino Fundamental. Para tal propósito, é apresentado um recorte de uma pesquisa de doutorado de abordagem qualitativa, com características de pesquisa-ação, desenvolvida com cinco professoras dos anos iniciais do Ensino Fundamental (...) de uma escola estadual de São Paulo, que participaram de uma formação continuada que teve como princípios teóricos e práticos a Educação Matemática Crítica e a Educação Libertadora. Por um período de nove meses, ao longo de quinze encontros, dialogou-se a respeito de temas advindos dos saberes de experiência das docentes e de suas relações com o contexto educacional. A ideia de dialogar a respeito desses temas permitiu não só tomar consciência da realidade, mas também construir ações visando a transformação da prática pedagógica. Desse modo, os diálogos estabelecidos entre as participantes e a pesquisadora também deram abertura para que o ensino da matemática fosse refletido e discutido nos termos da Educação Matemática Crítica. Os dados produzidos ao longo da formação continuada foram analisados e interpretados à luz da Análise Dialógica do Discurso, oriunda dos estudos bakhtinianos. Os resultados desta investigação mostraram que a escola se encontrava submetida a uma burocratização do sistema escolar que, por meio das relações de poder, submetia as docentes participantes a normas e hierarquias que resultavam, na percepção delas, em situações-limite que, a princípio, não poderiam ser superadas. A partir dessa constatação, identificou-se que o principal desafio do desenvolvimento do processo de empoderamento é romper com a perspectiva de que as situações vivenciadas pelas docentes participantes não podem ser superadas. Mas, na medida em que as situações apresentadas são problematizadas, em que a realidade é desvelada e entendida como problemas, esses desafios transformam-se em possibilidades de ação e superação. (shrink)

O artigo procura abordar como produtos audiovisuais sobre cenas do metal em territórios africanos ao mesmo tempo em que se propõem a divulgar um outro olhar sobre as culturas africanas, também parecem reproduzir os discursos ocidentais construídos historicamente sobre suas sociedades e suas culturas locais. Para tanto, realizaremos uma análise fílmica do documentário Death Metal Angola, a qual apresentou mundialmente a existência de uma rede musical angolana dedicada ao subgênero death metal. Refletiremos até que ponto as economias, as sociedades e (...) as culturas africanas, cujas histórias têm sido retratadas constantemente de forma pessimista pela mídia internacional, estão sendo reimaginadas pelo cenário global-local através desse produto fílmico. (shrink)

O presente artigo discute sobre o caráter aberto que Ricœur, em sua obra A memória, a história, o esquecimento, mantém para a questão da validade da historiografia enquanto saber científico. O fato de Ricoeur não objetivar um consenso que valide a historiografia, no sentido epistemológico, pode desanimar um leitor historiador. No entanto, o dissensus que se reflete na falta de um método paradigmático, de um significado unívoco e de uma categoria fundamental da investigação historiográfica, em Ricoeur, não condena a historiografia (...) à impossibilidade. Ao invés disso, o presente texto tem o objetivo de justificar o caráter “aberto” da historiografía, exposto por Ricoeur na obra aqui citada, apresentando a necessidade das “perspectivas cruzadas” para a relação da historiografia com o debate público. Essa discussão desemboca nas implicações éticas e políticas do discurso historiográfico. (shrink)

This review presents a state of the art in artificial intelligence applied to urban planning and particularly to land-use predictions. In this review, different articles after the year 2016 are analyzed mostly focusing on those that are not mentioned in earlier publications. Most of the articles analyzed used a combination of Markov chains and cellular automata to predict the growth of urban areas and metropolitan regions. We noticed that most of these simulations were applied in various areas of China. An (...) analysis of the publication of articles in the area over time is included. (shrink)

ResumoAs práticas culturais fundem, a todo o momento, diferentes relações entre sistemas culturais (EVEN-ZOHAR, 1990) que antes eram separados. Tais manifestações híbridas reconfiguram e desterritorializam processos simbólicos. Nesse sentido, o presente artigo realiza uma análise comparatista das relações intertextuais presentes na configuração artística do álbum Esú, do rapper brasileiro Baco Exu do Blues, em especial na faixa “Capitães de Areia” em relação ao romance quase homônimo de Jorge Amado, às referências à mitologia dos Erês, e à série fotográfica Laróyè, de (...) Mario Cravo Neto. Para analisar as implicações dessas inter-relações na configuração cultural e identitária da obra, buscamos aporte teórico-crítico no campo dos Estudos Culturais pela perspectiva de conceitos que tentam dar conta desses processos, acerca do Hibridismo, em Néstor García Canclini, e das reflexões sobre sincretismo religioso em Sérgio Ferretti.Palavras-chave: Capitães da Areia; Hibridismo; sincretismo religioso; práticas culturais. AbstractCultural practices merge, at all times, different relationships with cultural systems (EVENN-ZOHAR, 1991) that were previously separated. Such hybrid manifestations reconfigure and deterritorialize symbolic processes. In this sense, this article performs a comparative analysis of the intertextual relations present in the artistic configuration of the album Esú, by rapper Baco Exu do Blues, especially the track “Capitães de Areia” and references to the mythology of the Erês, to the novel by Jorge Amado and Laróyè photographic series by Mario Cravo Neto. To analyze the implications of these interrelations in the cultural and identity configuration of the work, we seek theoretical-critical support in the field of Cultural Studies from the perspective of concepts that try to account for these processes, about Hybridism in Néstor García Canclini and reflections on religious syncretism in Sérgio Ferreti.Keywords: Capitães da Areia; Hybridity; religious syncretism; cultural practices. (shrink)

A pandemia de COVID-19 já levou à morte mais de cem mil brasileiros. A doença impõe um debate sobre o papel do Estado na segurança alimentar e na agricultura sustentável, que foram diretamente atingidas pelo isolamento social. O presente artigo, fruto a pesquisa exploratória doutrinária, objetiva fundamentar atuação do Poder Público durante a pandemia, pelo Princípio da Fraternidade, para a realização do Objetivo de Desenvolvimento Sustentável 02 da Organização das Nações Unidas, que prevê metas para erradicação da fome, melhoria da (...) segurança alimentar, da nutrição e da agricultura sustentável. (shrink)

Neste trabalho, explicamos de que maneira a teoria do filósofo inglês do século XVII, Thomas Hobbes, pode ser aproveitada e aplicada, com as devidas proporções e limitações, ao atual contexto de pandemia no que circunscreve o Brasil. Mais especificamente, analisaremos a situação atual a partir de casos concretos do fenômeno definido como bolsonarismo, termo utilizado para se referir às políticas e à ideologia do atual Presidente da República Federativa do Brasil e seus filhos. Os seguidores do bolsonarismo são conhecidos por (...) tratarem o presidente como uma espécie de herói que irá salvar a nação. Levando em consideração a teoria hobbesiana de origem contratual do Estado Moderno – visto que este último é a base política do Ocidente – em nossa investigação, iremos recorrer aos princípios propostos pelo filósofo seiscentista para avaliar as possíveis causas que levariam ao esfacelamento do Estado brasileiro frente à atual crise governamental agravada e gerada pela pandemia do novo coronavírus. Além disso, abordaremos a necessidade de dois elementos hobbesianos basilares para assegurar a soberania estatal plenamente: a autoridade política e a liberdade republicana. A posição defendida pelo autor será estudada a partir do _Leviatã_, obra que concentra a maior parte das discussões hobbesianas acerca da desobediência civil, em conjunto, certamente, com outros comentadores de peso e demais referenciais teóricos pertinentes. Por fim, trata-se de um convite à desobediência civil, associado a um autor que constrói a sua teoria a partir da submissão de súditos a um poder soberano. (shrink)

Resumo: Focamos neste trabalho algumas das tensões vivenciadas por professores pesquisadores vinculados ao sistema de Pós-graduação brasileiro, no contexto das transformações recentes da universidade. Os protagonistas da PG buscam alternativas éticas para o que consideram descaminhos na produção de conhecimentos no contexto científico. O trabalho decorre dos resultados de um conjunto de pesquisas sobre temas associados à produção em nível stricto sensu, desenvolvidas na última década por diversos pesquisadores em grupos ou projetos de investigação. Os resultados vêm mostrando cada vez (...) maior interferência de organismos nacionais de regulação, controle e avaliação do sistema de PG no funcionamento da universidade, ferindo a sua autonomia. Em consequência, os professores pesquisadores que atuam na PG veem-se compelidos a obedecer a dois ‘patrões’, ou ‘senhorios’, cujas exigências são distintas e não raro antagônicas. Diante dos frequentes conflitos entre as exigências, prevalece a subserviência ao órgão externo, já que as próprias IES estão sob avaliação destes órgãos. Neste contexto, emerge o debate sobre a excelência da produção acadêmico-científica, trazendo-se à tona os limites da produção/produtivismo. Como contribuição trazemos a noção de pertinência territorial para pensar outra possível modalidade de excelência. Por fim, enriquecemos a discussão da problemática, a partir da perspectiva do pensamento decolonial, que envolve a crítica ao eurocentrismo vigente em nossa academia e propõe o ‘penso onde sou’ como caminho para que a produção científica encontre alternativas, conectadas com as realidades e necessidades dos territórios em que estão instaladas as universidades e seus programas de PG. (shrink)

O objetivo desta publicação é incentivar a produção filosófica de excelência por parte de pesquisadores notadamente influenciados pela filosofia de Wittgenstein e cujos temas possam suscitar um debate aprofundado. Além de desafiar o empreendimento filosófico contemporâneo, os temas aqui apresentados abordam questões que muitas vezes estão além daquelas consideradas por Wittgenstein em seu tempo. O leitor encontrará neste volume questões relacionadas ao ceticismo semântico e epistêmico, ao relativismo ético, às leituras literárias de Wittgenstein, ao problema das outras mentes e percepção (...) de aspectos, a intersubjetividade e o caráter contrassensual do Tractatus Logico-Philosophicus, e, também, relacionadas ao Paradoxo de Moore. (shrink)

Trata-se de analisar em que medida convergem os autores Bacon e Descartes no que diz respeito ao progresso das ciências, e como constituem um ideal de ciência na modernidade. O cenário que se constituía na Europa em meados do século XVII era de reconfiguração, de redescoberta e de inventos. Apesar de as artes mecânicas, as artes marítimas e as artes eruditas receberem, em alguma medida, um impulso para o novo, a ciência era ainda influenciada pela escolástica. A ela se oporiam, (...) de maneiras diferentes, Bacon e Descartes, com a finalidade de viabilizar o progresso das ciências. É evidente que se encontra, nos autores propostas dissemelhantes para que o progresso das ciências ocorra: para um o experimento é imprescindível e para o outro o uso da razão é fundamental. Neste artigo, entretanto, será investigado como posicionam-se Bacon e Descartes em três partes: 1- As preocupações para o avanço do conhecimento, 2-Os novos métodos e suas consequências, e, por fim, 3- Da finalidade do avanço das ciências. Ficará evidente, em cada parte, que, apesar das dissonâncias entre suas filosofias, há vários pontos em que convergem no que diz respeito ao progresso das ciências, como é o caso, por exemplo, do uso da natureza, da técnica, da importância de Deus e das escrituras para enfatizar como a possibilidade do progresso estava em consonância com o que o Criador permitia ao homem. Ficará evidente, também, como, a partir dos pontos aos quais convergem Bacon e Descartes, pode-se observar o estabelecimento de certo ideal de ciência na modernidade. (shrink)

As características do ambiente no qual o organismo é exposto podem exercer influências que favorecem ou prejudicam seu desenvolvimento. A família pode ser considerada como o primeiro grupo social com o qual a criança interage e exibe papel privilegiado neste processo. O presente estudo pretendeu descrever e comparar a interação entre as díades mãe-bebê em situação lúdica e na troca de fraldas. Participaram 20 mães de bebês de quatro a seis meses de idade. Para a codificação das interações utilizou-se o (...) Sistema de Codificação da Interação Mãe-Criança Revisado (CITMI-R). Os resultados apontaram que nas duas situações o comportamento materno mais frequente foi o Sensível Neutro e dos bebês foram os de Aproximação Social Neutra e de Jogo. Na situação de cuidado as mães apresentaram, também, o comportamento Protetor Positivo. Conclui-se que houve baixa frequência de comportamentos interativos positivos, apontando para a importância de intervenções junto às mães de bebês. (shrink)

Resumo: Este estudo objetiva analisar as perspectivas de futuros professores em relação às práticas pedagógicas necessárias para a inclusão de alunos com deficiência, assim como a possibilidade de construí-las no cotidiano escolar. Para participar da pesquisa, foram selecionadas dezesseis futuras professoras que estão cursando os últimos semestres do curso de Pedagogia e já atuam como estagiárias na Educação Básica. A pesquisa se fundamenta na abordagem qualitativa e utilizou as narrativas como instrumento da coleta de dados. A partir do processo de (...) análise textual discursiva, identificaram-se três dimensões, com base nas temáticas utilizadas nesse estudo: Educação Inclusiva; Práticas Pedagógicas Inclusivas; Experiência. Os resultados do estudo indicam as experiências das professoras como novas e significativas e que o elemento principal para a transformação da educação inclusiva passa pela necessidade de formação, estudos e trocas de experiências e de constante construção teórico-prática, que se faz mister no processo inclusivo. Palavras-chave: Educação Superior; Educação Inclusiva; Formação de Professores; Práticas Pedagógicas. The perspectives of Inclusive Education in the Education course: narratives of beginning teachers Abstract: This study aims to analyze the perspectives of future teachers in relation to the pedagogical practices necessary for the inclusion of students with disabilities, as well as the possibility of building them in the school routine. In order to participate in the research, sixteen future teachers who are attending the last semesters of the Education course and already work as interns in Basic Education were selected. The research is based on a qualitative approach and it uses narratives as an instrument for data collection. From the discursive textual analysis process, three dimensions were identified, based on the themes used in this study: Inclusive Education; Inclusive Pedagogical Practices; Experience. The results of the study indicate the experiences of the teachers as new and significant, and that the main element for the transformation of inclusive education involves the need for training, studies and exchanges of experiences as well as constant theoretical-practical construction, which is essential in the inclusive process. Keywords: Higher Education; Inclusive Education; Teacher Training; Pedagogical Practices. Las perspectivas de la Educación Inclusiva en el curso de Pedagogía: narrativas de profesores principiantes Resumen: Este estudio tiene por objetivo analizar las perspectivas de futuros profesores con relación a las prácticas pedagógicas necesarias para la inclusión de alumnos con discapacidad, así como la posibilidad de construirlas en el cotidiano escolar. Para participar de la pesquisa, fueron seleccionadas dieciséis futuras profesoras que están cursando los últimos semestres del curso de Pedagogía y ya actúan como pasantes en la Educación Básica. La investigación se fundamenta en un enfoque cualitativo y utilizó las narrativas como instrumento de recogida de dados. A partir del proceso de análisis textual discursivo, fueron identificados tres dimensiones, con base en las temáticas utilizadas en este estudio: Educación Inclusiva; Prácticas Pedagógicas Inclusivas; Experiencia. Los resultados del estudio indican las experiencias de las profesoras como nuevas y significativas y que el elemento principal para la transformación de la educación inclusiva pasa por la necesidad de formación, estudios y cambios de experiencias además de constante construcción teórico-práctica, que es esencial en el proceso inclusivo. Palabras clave: Educación Universitaria; Educación Inclusiva; Formación de Profesores; Prácticas Pedagógicas. Data de registro: 14/04/2021 Data de aceite: 19/01/2022. (shrink)

O objetivo central do trabalho é analisar a posição evolucionista proposta por Michael Ruse a respeito da ética no âmbito de primeira e de segunda ordem. Para cumprir com este objetivo, inicialmente distinguiremos a posição evolucionista de Ruse, de fundamentação darwiniana, com a posição evolucionista clássica, de fundamentação spenceriana. Mostraremos como Ruse inicialmente reformula a ética evolucionista spenceriana, tornando o âmbito da ética substantiva descritivo, e não mais prescritivo, a partir da compreensão correta do conceito de altruísmo. No âmbito da (...) metaética, mostraremos como Ruse desenvolve uma posição evolucionista sem recair nos problemas clássicos da lei de Hume e da falácia naturalista. Por fim, mostraremos que a metaética darwiniana de Ruse pode ser considerada como um tipo de teoria do erro. Concluiremos que a proposta de ética e metaética darwiniana de Ruse trazem grandes avanços para a discussão, fortalecendo a importância da biologia na investigação tradicionalmente filosófica. (shrink)

The political and financial investments in the implementation of forensic DNA databases and the ethical issues related to their use and expansion justify inquiries into their performance and general utility. The main function of a forensic DNA database is to produce matches between individuals and crime scene stains, which requires a constant input of individual profiles and crime scene stains. This is conditioned, among other factors, by the legislation, namely the criteria for inclusion of profiles and the periods of time (...) and conditions for their retention and/or deletion. This article aims to provide an overview of the different legislative models for DNA databasing in Europe and ponder if wider inclusion criteria – and, consequently, database size – translates into more matches between profiles of crime scene stains and included individuals. The legislation governing forensic DNA databases in 22 countries in the European Union was analysed in order to propose a typology of two major groups of legislative criteria for inclusion/retention of profiles that can be classified as having either expansive effects or restrictive effects. We argue that expansive criteria for inclusion and retention of profiles do not necessarily translate into significant gains in output performance. (shrink)

This book is dedicated to clarify ambiguous concepts from the world of creativity and innovation. One of the initial triggers for the development of the book was the perceived ambiguity of the binomials Design vs. Design Thinking and Innovation vs. Invention. Frequently, designers and innovation consultants are questioned by their clients about the relationships between these kind of concepts. Has the second emerged through the first, or vice-verse? Is one part of the other? Where are the similarities and which are (...) the differences? This conceptual incomprehension makes itself noticeable between many ambiguous concepts in the world of innovation and creativity. What is the difference between Radical and Disruptive Innovation? Or is Social Innovation the same as Social Intervention? And regarding Creativity, are Creativity and Creative Thinking the same? In this book the reader will find answers to these kinds of questions and doubts. 28 authors from 10 different countries and cultural backgrounds are questioning current definitions and perceptions, by comparing different sources and ideas, or simply by giving their personal opinions. Some of the authors have an academic background, others a practical one, being either entrepreneurs, working with innovation in companies, or being innovation/design consultants. (shrink)

Tem-se por objetivo, (a) caracterizar comportamentos de 47 cuidadores primários e de seus filhos que buscaram atendimento, (b) comparar grupos, abandono x participantes, menino x menina. Os participantes responderam à entrevista (RE-HSE-P), inventário (IHS-Del Prette) e escalas (Escala de Assertivid..

The imposition of telework due to the COVID-19 pandemic brought with it the need for individuals to readjust their work-non-work boundaries. In this crisis situation, individuals’ needs to manage these boundaries may have been influenced by contextual factors, such as family-supportive supervisor behaviors and macro-structural aspects, such as the country to which the teleworkers belong. This study tests the mediating effect of boundary control on the relationship between FSSB and satisfaction with life and examines the moderating effect of the country (...) in the relationship between FSSB and boundary control. With a sample of 108 Portuguese and 118 Pakistani individuals, the results were analyzed using Process tool. FSSB was found to be important for teleworkers to control their boundaries and for their satisfaction with life and this control was also seen to contribute to higher levels of life satisfaction. Differences between the two countries were observed: boundary control mediates the relationship between FSSB and satisfaction with life for Pakistani teleworkers and these workers are more dependent on FSSB to exercise boundary control than Portuguese teleworkers. This study highlights the importance of considering contextual factors when implementing telework. Practical implications are discussed. (shrink)

The central hypothesis of the collaboration between Language and Computing (L&C) and the Institute for Formal Ontology and Medical Information Science (IFOMIS) is that the methodology and conceptual rigor of a philosophically inspired formal ontology greatly benefits application ontologies. To this end r®, L&C’s ontology, which is designed to integrate and reason across various external databases simultaneously, has been submitted to the conceptual demands of IFOMIS’s Basic Formal Ontology (BFO). With this project we aim to move beyond the level of (...) controlled vocabularies to yield an ontology with the ability to support reasoning applications. Our general procedure has been the implementation of a meta-ontological definition space in which the definitions of all the concepts and relations in LinKBase® are standardized in a framework of first-order logic. In this paper we describe how this standardization has already led to an improvement in the LinKBase® structure that allows for a greater degree of internal coherence than ever before possible. We then show the use of this philosophical standardization for the purpose of mapping external databases to one another, using LinKBase® as translation hub, with a greater degree of success than possible hitherto. We demonstrate how this offers a genuine advance over other application ontologies that have not submitted themselves to the demands of philosophical scrutiny. LinKBase® is one of the world’s largest applications-oriented medical domain ontologies, and BFO is one of the world’s first philosophically driven reference ontologies. The collaboration of the two thus initiates a new phase in the quest to solve the so-called “Tower of Babel”. (shrink)

The central hypothesis of the collaboration between Language and Computing (L&C) and the Institute for Formal Ontology and Medical Information Science (IFOMIS) is that the methodology and conceptual rigor of a philosophically inspired formal ontology greatly benefits application ontologies.[1] To this end LinKBase®, L&C’s ontology, which is designed to integrate and reason across various external databases simultaneously, has been submitted to the conceptual demands of IFOMIS’s Basic Formal Ontology (BFO).[2] With this project we aim to move beyond the level of (...) controlled vocabularies to yield an ontology with the ability to support reasoning applications. Our general procedure has been the implementation of a meta-ontological definition space in which the definitions of all the concepts and relations in LinKBase® are standardized in a framework of first-order logic. In this paper we describe how this standardization has already led to an improvement in the LinKBase® structure that allows for a greater degree of internal coherence than ever before possible. We then show the use of this philosophical standardization for the purpose of mapping external databases to one another, using LinKBase® as translation hub, with a greater degree of success than possible hitherto. We demonstrate how this offers a genuine advance over other application ontologies that have not submitted themselves to the demands of philosophical scrutiny. (shrink)

ObjectiveThis study aims to analyze sociohistorically how the normative patterns of hegemonic masculinity produced impacts on men’s health/mental health in the context of the COVID-19 pandemic.MethodsA qualitative study from a socio-historical perspective was conducted with 50 men based on an online survey. A semistructured form was applied. The data were analyzed by the Collective Subject Discourse method, interpreted in the light of the context of epidemic disease and hegemonic masculinity.ResultsThe experience of the pandemic exposed the normative patterns of masculinities from (...) the consummation of acts representative of the pandemic context, which incited men to deny the existence of COVID-19 disease and to delay the understanding and adoption of measures to protect and control COVID-19. As a repercussion, men presented conflicts in the regulation of emotions; presented emotional suppression; were more reactive; felt threatened regarding the loss of the role of family provider, virility; and revealed a sense of invulnerability, added to the weakening of self-care.ConclusionThe discourse revealed that the men’s behaviors are consistent with the characteristics of hegemonic masculinity, but express signs of recognition that this behavior causes harm to themselves and their health. (shrink)

Esse artigo expõe as principais características das filosofias do dever moral e daquelas que explicam a ação humana a partir do sentimento moral. Essas filosofias são opostas em muitos pontos, mas coincidem na contraposição entre sentidos e razão humanos. Ambas as propostas filosóficas têm repercussões na Ética, no Direito e na Pedagogia, os quais acabam recebendo forte influência racionalista ou sentimentalista. Confrontamos esses dois sistemas com a atual “Ética das Virtudes”, a qual pretende sair do impasse surgido do debate entre (...) as duas teorias anteriores a partir do redescobrimento de pensadores como Aristóteles e Santo Tomás de Aquino. Atualmente, a Ética das Virtudes assume a colaboração de pesquisadores de diversas ciências contemporâneas, tais como a Sociologia, a Neurociência e a Filosofia Política. (shrink)

A literatura infantil encontra-se povoada de personagens femininas como figuras centrais de narrativas, algumas delas, famosas e populares. A partir de 1980, surgiram autores que apresentam obras de reconhecido valor estético, nas quais personagens femininas mirins têm um lugar de destaque. Fala-se, por exemplo, de Isabel (Bel), personagem narradora da obra Bisa Bia, Bisa Bel (1981), de Ana Maria Machado, que percorre um caminho rumo à autonomia. O presente trabalho volta-se para a representação de um sujeito feminino que, ainda (...) em tenra idade, consegue estabelecer um diálogo entre épocas diferentes, apresentando visões diversas da mulher, uma antiga, Bisa Bia, típica do século XIX, e outra, Bel, moderna, independente, do fim do século XX. (shrink)

Resumo: Palavras-chave: : Keywords: Child literature. Female subject. Representation. The child literature is inhabited by female characters as central figures of the narrative, some of them famous and popular. The decade of 1980 saw the raise of authors who introduce works that have recognized aesthetic value in which female characters play a prominent role. For example, Isabel (Bel), narrator character from the work Bisa Bia, Bisa Bel (1981), by Ana Maria Machado, who is lead through a path toward her (...) autonomy. This paper is concerned with the representation of a female subject who even in its early age is able to establish a dialogue between different epochs, presenting different women perspectives, the old one, Bisa Bia, XIX century representative, and the other one, modern, independent, from the late XX century. Literatura infantil. Sujeito feminino. Representação. A literatura infantil encontra-se povoada de personagens femininas como figuras centrais de narrativas, algumas delas, famosas e populares. A partir de 1980, surgiram autores que apresentam obras de reconhecido valor estético, nas quais personagens femininas mirins têm um lugar de destaque. Fala-se, por exemplo, de Isabel (Bel), personagem narradora da obra Bisa Bia, Bisa Bel (1981), de Ana Maria Machado, que percorre um caminho rumo à autonomia. O presente trabalho volta-se para a representação de um sujeito feminino que, ainda em tenra idade, consegue estabelecer um diálogo entre épocas diferentes, apresentando visões diversas da mulher, uma antiga, Bisa Bia, típica do século XIX, e outra, Bel, moderna, independente, do fim do século XX. (shrink)

A mineradora Vale S.A., ativamente atuante na região de Mariana e Ouro Preto, no Estado de Minas Gerais, idealizou um projeto direcionado à Educação Patrimonial que durante 8 anos foi considerado como um dos principais projetos com viés cultural da região. Neste contexto, considerando que a Educação Patrimonial é de extrema importância para a formação da identidade cultural e social do indivíduo autônomo, objetiva-se analisar, sob a perspectiva crítica, as inter-relações entre o Programa de Educação Patrimonial Trem da Vale (...) com o conceito que carrega a Indústria Cultural, conforme cunhado pelos teóricos críticos Theodor Adorno e Horkheimer no livro “Dialética do Esclarecimento” (1985). Para tanto, para a realização da análise empírica utilizou-se como categoria de sentido a tese de Francisco Rüdiger (2004) sobre os esquematismos interpretativos comumente presentes nas práticas da Indústria Cultural. (shrink)

Los modelos de escritura están experimentando grandes transformaciones como consecuencia de la revolución tecnológica contemporánea. Aunque los cibertextos y los hipertextos no son realidades exclusivas de la cultura digital, pues se dan en contextos culturales precedentes, aportan formas de pensamiento alternativas, que pasan por implicaciones epistemológicas –el pensamiento en red–, estéticas –reformulación de la autoría– y éticas –exigen un compromiso por parte del receptor. En este trabajo se abordará dicha coyuntura comparando las escrituras literarias Hypertext Hotel (1992) y Leyenda mayor (...) de Ian Curtis (2017) con las escrituras audiovisuales +101 (2012) y Quién lo impide (2018) con el objetivo de comprender las transformaciones que suponen tanto en la experiencia estética como en el campo cultural digital. Para ello, se empleará una metodología comparatista que tenga en cuenta las concomitancias entre las dos series de escrituras. (shrink)

Currently there are persistent doubts about the meaning and contributions of the gene concept, mostly related to its interpretation as a stretch of DNA encoding a single functional product, i.e., the classical molecular gene concept. There is, however, much conceptual variation around genes, leading to important difficulties in genetics teaching. We investigated whether and how conceptual variation related to the gene concept and gene function models is present in school science and what potential problems it may bring to genetics teaching (...) and learning. Here, we report results on how ideas about genes and gene function are treated in textbooks and appear in students’ views and, also, about a teaching strategy for improving higher education students’ understanding of scientific models and conceptual variation around genes and their functions. (shrink)

IntroductionTranscranial magnetic stimulation is a consolidated procedure for the treatment of depression, with several meta-analyses demonstrating its efficacy. Theta-burst stimulation is a modification of TMS with similar efficacy and shorter session duration. The geriatric population has many comorbidities and a high prevalence of depression, but few clinical trials are conducted specifically for this age group. TBS could be an option in this population, offering the advantages of few side effects and no pharmacological interactions. Therefore, our aim is to investigate the (...) efficacy of TBS in geriatric depression.Clinical trial registration[https://clinicaltrials.gov/ct2/], identifier [NCT04842929]. (shrink)